• Title : A variety of dermatological treatment using cryodevice, Iontophoresis, and Choline
• Date : 11/30(Sat), at 13:40
• Room : EXCO Room 322

• Title : [Live Surgery] Application of botulinum toxin
• Date : 12/01(Sun), at 15:00
• Room : Room 322 (JCI allforskin Dermatologic Hospital)

[Dermatolocial Application with Botulinum Toxin, Iontophoresis, and Choline]

Botulinum toxin is made from a toxin of Clostridium botulinum. Botulinum toxin was used in the field of ophthalmology in 1970s and after then, its use has expanded to the field of dermatology. Botulinum toxin consists of 7 types of neurotoxins and clinically, only toxins A and B are used. At first, onabotulinum toxin A was introduced to the market. It has been used as a cosmetic treatment for reducing facial wrinkles: glabellar frown lines, crow’s feet around orbits, wrinkles around the lips and marionette lines. After botulinum toxin injection, it diffuses into the muscles until it binds selectively and reversibly in the presynaptic terminal of the neuromuscular junction and then attaches to the specific protein-membrane responsible for acetylcholine excretion. Botulinum toxin inhibits the release of acetylcholine in the neuromuscular junction causing reduction of muscle contraction. Contraindications for the treatment with botulinum toxin include myasthenia gravis, pregnancy, breastfeeding, neonate and children, focal and systemic infections, hypersensitivity or allergy to botulinum toxin. Adverse events occurring on the injection sites of botulinum toxin include bleeding, swelling, erythema and pain. Ecchymosis and purpura can be minimized by compressing ice on the injection sites. Other side effects include headache, malaise, nausea, influenza-like symptoms and ptosis.
Hyperhidrosis is heavy sweating that reduces patients' quality of life, leading to social and work impairment and emotional distress. Hyperhidrosis can be classified into primary and secondary hyperhidrosis: primary hyperhidrosis is bilaterally symmetric, focal, excessive sweating of the axillae, palms, soles, or craniofacial region not caused by other underlying conditions and secondary hyperhidrosis may be focal or generalized, which is caused by an underlying medical condition or medication use. Topical aluminum chloride solution can be used as a first-line treatment for the treatment of primary hyperhidrosis. In addition, botulinum toxin injection (onabotulinumtoxin A) is considered first- or second-line treatment for primary hyperhidrosis. Iontophoresis, oral anticholinergics, local microwave therapy, and local surgery and endoscopic thoracic sympathectomy are useful in some cases of hyperhidrosis. I would like to introduce neuronox as a kind of botulinum toxin for the treatment of axillary hyperhidrosis. In addition, I will show you how to block peripheral nerves, including ulnar nerve, median nerve, and radial nerve, for the treatment of palmar hyperhidrosis with botulinum toxin. Furthermore, I will make a presentation entitled “Open Clinical Trial for Evaluation of Efficacy and Safety of a Portable Dry-Type Iontophoretic Device in Treatment of Palmar Hyperhidrosis”. Effects of a new iontophoretic device for the treatment of palmar hyperhidrosis will be found.
A shapely body is everyone’s desire. Liposuction to reduce subcutaneous fat has been used most commonly in the cosmetic surgery procedure. However, liposuction is expensive, and has a theoretical risk of life-threatening complications. Nonsurgical alternatives to liposuction in common practice are cryolipolysis, radiofrequency ablation, HIFU (high-intensity focused ultrasound), and injection lipolysis. Lipolytic drug to induce a nonsurgical fat reduction has been used for clients seeking nonsurgical alternatives for the areas that may not be amenable to conventional liposuction. Phosphatidylcholine and deoxycholate injections have been introduced as nonsurgical alternatives to liposuction for the clients. Deoxycholate as a constituent for lipolysis has recently been approved by the US Food and Drug Administration. I would like to introduce choline as an alternative to liposuction.

- Assistant Professor, Hallym University 2000.5-2004.3
- Research Fellow, Department of Dermatology, University of Michigan
2007.9-2009.6
- Professor, Kyungpook National University 2004.5-present

• Title : [Live Surgery] The latest trends in dermatological anti-aging treatments: Treatment of wrinkle with filler
• Date : 12/1(Sun) at 16:00
• Room : Room 322 (JCI allforskin Dermatologic Hospital)

[The latest trends in dermatological anti-aging treatments: Treatment of wrinkle with filler]

The nasolabial fold is the deep crease running from either side of the nose down towards the corners of the mouth. This crease becomes more noticeable as part of the natural aging process. Fat is lost from the cheeks, reducing skin volume and making this fold appear deeper. Fillers are a very safe and effective modality for improving the nasolabial fold with minimal risks.
Deep nasolabial folds and marionette line can be corrected through injections of dermal filler into the surrounding area, restoring the lost volume and softening the appearance of these creases. The goal of nasolabial fold and marionetter injections is to even out the skin volume, leaving you with a smoother, refreshed-looking appearance. Nasolabial folds and marionette are best treated with dermal fillers on the level of subcutaneous layers. In the lecture, the easy and best treatment method will be showed.

- Vice President of the Daegu Medical Association
- President of Daegu Medical, Tourism, Industry Committee
- President of Association of Daegu Gyeongbuk Dermatologists
- The Chairperson & Special Lecture of 22nd World Congress of Dermatology

• Title : All-Round Skin Treatment, Cryotherapy : Oldest but Goodest
• Date : 11/30(Sat), at 17:0
• Room : EXCO Room 322

[All-Round Skin Treatment, Cryotherapy : Oldest but Goodest]

Cryotherapy is a widely used and effective treatment modality for various dermatologic disorders including immune-related skin diseases, such as itching,
Atopic dermatitis, and psoriasis. Conventional cryotherapy has limitations on the appropriate control of the skin surface temperature and standardization of treatment protocols, resulting in the possibility of serious thermal injury. Therefore, cryotherapy is limited in immunerelated skin diseases and is used to treat warts or other skin tumors where extremely low temperatures are needed for tissue destruction. Recently, a new devices that can precisely estimate and promptly control the temperature of the skin surface have been developed. Therefore, cryotherapy can be safely used to treat various immune-related skin diseases that have been difficult to treat by conventional cryotherapy. In the lecture, I would like to introduce various dermatologic problems which solved using cryotherapy.

[Future Cosmeceuticals : The Era of Skin Microbiome]

The skin's primary role is to act as a physical barrier that protects our body from attack by other organisms or harmful substances. The skin is also in direct contact with the external environment, so various microorganisms, including bacteria, fungi, and viruses, exist on the skin. The microorganisms living inside and outside the human body are referred to as the microbiome, and the entire microorganisms present on the skin surface are called the “skin microbiome.”
Some of the skin microbiome acts as pathogens, but most microorganisms are harmless to the human body, and skin flora and commensal bacteria suppress and control infection by pathogenic bacteria and support innate or adaptive immune response. It is known to play an important role in regulating The skin microbiome changes due to various environmental and external factors, and the skin maintains a complex balance between the host and various microorganisms. If this balance is destroyed, skin diseases or infections can occur.
Skin microbiome research is a research field that has recently attracted attention, and research results can be used for industrial and public purposes in various fields.
A significant portion of microbiome research is focused on the relationship between intestinal bacteria and disease. The skin microbiome is simpler to sample than the intestinal microbiome and is closely related to an individual's health and external environment, so various biological information about an individual can be obtained.
Among the environmental factors that affect the skin, rays such as ultraviolet rays, visible rays, and infrared rays account for a large proportion. The skin performs useful functions such as the synthesis of vitamin D from the various rays transmitted from the sun, but on the other hand, the skin's role as an organ that prevents excessive exposure to rays is very important. This is called barrier function, and damage to barrier function is known to be the cause of various skin diseases and skin cancer. However, research on changes in the skin microbiome depending on the type, wavelength, and exposure time of light is insufficient, and active research is needed in the future.

• Medical officer in Marine Corps , South Korea; 1999~2000
• Medical officer in Presidental Security service, South Korea; 2000~2002
• Clinical Assistant Professor, Department of Dermatology, Samsung Medical Center, South Korea; 2004~2007
• Professor , Department of Dermatology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, South Korea; 2007~
• Chairman of Dermatology Department of Kangbuk Samsung Hospital, South Korea; 2007~2019
• General Director of R&D Management Department of Kangbuk Samsung Hospital; 2017~2021
• General Director of Planning Department of Kangbuk Samsung Hospital; 2021~

• Title : [Cosmeceuticals] Pro Tips for Combining Dermatological Medications with Lasers in Pigment Treatment
• Date : Nov 30(Sat), 10:00
• Room : EXCO Room 322

[Pro Tips for Combining Dermatological Medications with Lasers in Pigment Treatment]

Navigating the complexities of pigmentation disorders, notably melasma, one cannot underestimate the potency of advanced dermatological drugs, particularly when paired with laser treatments. The sources of pigmentation extend beyond the expected culprits of ultraviolet rays, with visible light, particularly the blue spectrum, emerging as influential factors due to their interaction with opsin-3.
In addressing these concerns, tinted sunscreens from the iron oxide series prove beneficial. Moreover, the realm of cosmetology offers a rich palette of ingredients tailored for this challenge: from well-established agents like ascorbic acid, kojic acid, and retinol to the synergistic trio of tretinoin, hydroquinone, and steroids.
A standout in this therapeutic journey is tranexamic acid (trans-4-(aminomethyl) cyclohexane carboxylic acid), which counteracts the nuances of pigmentation. Its actions are manifold: stalling the conversion of plasminogen to plasmin, shielding keratinocytes, tempering arachidonic acid secretion, and decreasing the production of prostaglandin and fibroblast growth factor involved in melanin production. It also reduces melanin synthesis, mast cells, and angiogenesis. This efficacy is enhanced when paired with laser procedures, typically recommended at a 250 mg dosage, administered twice daily.
However, the use of tranexamic acid comes with certain considerations. Its compatibility is questionable in scenarios involving renal dysfunction, malignancies, cardiovascular or respiratory diseases, anticoagulant therapy, personal or family history of thromboembolic disease, and during pregnancy. It is also not recommended in conjunction with contraceptive pills, hormone replacement therapy, smoking, or during extended travels.
For those seeking a comprehensive approach, incorporating agents like melatonin, glutathione, ketotifen, and famotidine can further enhance the therapeutic outcomes. Through evidence-based and combined strategies, the path to addressing pigmentation becomes clearer and more achievable.

- Korean Society for Anti-Aging Dermatology, Executive Director
- Korean Dermatological Association, Assistant Director of Public Relations
- Korean Society for Skin Barrier Research, Academic Director
- Korean Medical Society for Cosmetics, Assistant Academic Director and Councilor

• Title : Application of chitosan on androgenetic alopecia
• Date : 11/30(Sat), at 10:50
• Room : EXCO Room 322

• Title : [Cosmeceuticals] Exosome based Hair Loss treatment
• Date : Dec 1(Fri), at 16:00
• Room : EXCO Room 324

• Title : [Sponsored Session] Effectiveness of Molecular Weight Controlled Chitosan on the Human Body
• Date : Dec 2(Sat) 13:00
• Room : EXCO Room 324

• Title : [Sponsored Session] All about Ell-Cranell on the Hair Loss
• Date : Dec 2(Sat) 13:20
• Room : EXCO Room 324

[Facial lifting using monopolar RF]

Background :
Monopolar radiofrequency(MRF) treatment is known to induce collagen contraction and remodeling in dermis.

Objective :
To evaluate safety of MRF in pre-clinical study first, and efficacy and safety in lifting and tightening of the face and upper neck, in the clinical study.
Methods & Materials
In pre-clinical setting, thermal imaging after the procedure, and clinical and dermoscopic photography of after the procedure, and 7, 14, 30 days later were recorded. In clinical study, 23 subjects were enrolled and got 1 treatment. They followed up at 4, 12, 24 weeks, and assessed using global photographic assessment, changes in elasticity, pore number, wrinkle(%), and safety evaluation was done.

Results :
In pre-clinical study, energy is safely delivered in treatment area. In clinical study, the clinical grades were significantly decreased after 4, 12, and 24 weeks. Net and biological elasticity significantly increased at week 24. Pore count significant decreased from week 12 and wrinkle(%) started to decrease from week 4. Subjective satisfaction was highest in week 12. The average of pain score was 0.30 0.63, and only mild adverse events were recorded.

Conclusion :
This study found that MRF deliver stable energy to the skin and have significant effect in skin laxity without complications.


[Exosome based hair loss treatment]

Introduction :
Androgenetic alopecia (AGA) is a common hair loss disorder mediated by dihydrotestosterone, which leads to the progressive miniaturization of hair follicles and psychological effects. Current treatment options have limitations, including unpredictability and side effects. Regenerative therapies, such as platelet rich plasma (PRP) and exosomes, have shown promise in promoting hair
growth. This study aimed to evaluate the effects of adipose derived stem cell exosomes (ASC exosomes) on hair follicle growth through preclinical and clinical studies.

Materials and Methods and Result :
In vitro Study: ASC exosomes were isolated and characterized. Human hair follicle dermal papilla4cells (hDPCs) were treated with ASC exosomes, showing incre ased proliferation and uptake. Expression of hair growth related genes and Wnt/β catenin pathway markers was upregulated. Hair follicle organ culture demonstrated increased hair shaft elongation, ALP activity, and Ki 67 and β
catenin expression in exosome treated groups.

Clinical Studies:
Thirty AGA patients underwent treatment with ASCE+HLRV Ⓡ , a solution of ASC exosomes. Hair density was measured using phototrichogram, showing significant increases in terminal and total hair density. Global photographic assessment and participant satisfaction surveys demonstrated significant improvements. No severe adverse reactions were reported.

Discussion:
This translational study suggests that ASC exosomes can effectively promote hair growth and provide a safe alternative for AGA treatment. While further randomized controlled trials are needed to confirm these findings, the preclinical and clinical data support the potential of exosome based therapies in hair restoration.

Conclusion:
Adipose derived stem cell exosomes have shown promising results in promoting hair growth both in vitro and in clinical studies. These findings highlight the potential of exosome based therapies as a safe and effective treatment for androgenetic alopecia, warranting further inv estigation.

[Effectiveness of Molecular Weight Controlled Chitosan on the Human Body]

Chitosan is a natural polymeric material with a structure similar to cellulose.
It is known as a natural bio material with great applicability in medicine and medical fields due to its biodegradability, biocompatibility, and non-toxicity as well as various pharmacological activities.
However, the bioactivity of final chitosan products are different based on the amount of deacytilation or particle size or water solubility.
So, chitosan should be adjusted to the molecular size that shows the best hysiological activity.In this lecture, I want to share the hair growth effect of low molecular weight water soluble chitosan based on the in vitro experiment and pilot clinical study.

[All about the Ell-Cranell on the Hair Loss]

The mechanism of action of Eclaenel on hair can be likened to that of 17β-estradiol (E2), and its action mechanism in the hair is as follows:

(1) Direct action on hair follicle and mammary gland cells
17β-estradiol can directly induce proliferation of mammary gland cells and has a concentration-dependent effect on increasing the length of hair follicles. Additionally, it influences the hair cycle by inducing the growth phase and preventing the transition to the regression phase. The impact on the hair cycle is empirically confirmed by the fact that estrogen during pregnancy reduces hair loss, lengthens the growth phase of hair, and postpartum hormonal changes lead to postpartum hair loss.

(2) Regulation of hair cycles through androgen and sex hormone metabolism
Testosterone is converted to Dihydrotestosterone (DHT) by 5a-reductase, which binds more strongly to the Androgen receptor and is known to induce androgenetic alopecia. In this process, 17β-estradiol inhibits the action of 5a-reductase, thereby suppressing the production of DHT and preventing androgenetic alopecia. Unlike men, women have a high expression of aromatase in the frontal scalp, which is known to be one reason why the frontal hairline is maintained even as hair loss progresses in women. 17β-estradiol is known to induce the activation of aromatase in growing hair follicles. Aromatase inhibits the conversion of testosterone to DHT and relatively increases the production of estadiol (E2), influencing the hair cycle and regeneration of hair follicles.

Therefore, therapies targeting 17β-estradiol can effectively be used in the treatment or prevention of androgenetic alopecia, and Eclaenel, based on its isomer and inactive component 17α-Estradiol, is expected to act effectively in hair loss treatment.

- Travel grant, 8th World Congress for Hair Research, 2014
- Travel grant, 23rd Meeting of World Congress of Dermatology, 2015
- Best Poster Presentation Prize, 26th International Society for Hair Restoration Surgery, 2018

• Title : [Injectables] Wrinkles treatment Using Botulinium toxin and Filler
• Date : 11/30(Sat), at 15:00
• Room : EXCO Room 322

• Title : Natural full face augmentation using PLLA
• Date : 11/30(Sat), at 15:20
• Room : EXCO Room 322

• Title : [Live Surgery] Procedures For Forehead and Temple Augmentation Using PLLA with HA
• Date : 12/01(Sun), at 10:00
• Room : Room 322 (JCI allforskin Dermatologic Hospital)

[Wrinkles treatment Using Botulinum toxin and Filler]

Injection with Botulinum toxin type A(BTX) is one of the most widely performed non invasive cosmetic procedures in the world. The first medical use of BTX - as reported in 1980, and the first cosmetic use of BTX-as a safe and effective treatment for glabellar lines- was described in a seminal paper published in 1992. The Food and Drug Administration granted approval for the treatment of facial wrinkles on April 12, 2002. Consensus recommendations for onabotulinum toxin type A ( Botox, Allergan, Inc., Irvine, CA) from the United States and for abobotulinum toxin type A ( Dysport, Ipsen Ltd, Slough, UK) from Europe began to arise in 004, and revised or updated consensus recommendations have recently been published to help physician treat Caucasians. In Asian countries, the use of BTX in cosmetic procedures started when the commercial preparation of BTX became available, roughly 1999. With ethnic differences in skin texture, facial muscle anatomy, pharmacologic reactions, and notions of beauty, it is difficult to apply consensus recommendations based on Caucasians directly to Asians.
Commercial preparations of BTX products that are available in Korea are Botox, Botulax(Hugel Inc., Chuncheon, Korea), BTX-A(Hugh Source, Hong Kong, China), Dysport, Neuronox(Medytox Inc., Seoul.Korea) ,and Xeomin(Merz Pharma GmbH & Co. KGaA, Frankfurt/Main, Germany)(in alpha betical order). Of these, only Dysport is abobotulinum toxin type A. It has different bacterial strains of origin, different methods of purification and stabilization, different chemical and biological properties, and different units(Speywood units) of potency. This product has mainly been used for facial aesthetics in Europe, whereas onabotulinum toxin type A products have most commoly been used in the United States. The dose equivalency of the products(Botox: product) are Botulax, 1:1 and BTX-A, 1:1; Dysport, 1:2-1:4; Neuronox, 1:1; and Xeomin,1:1. Botox and Neuronox are the most frequently used products in Korea, and as mentioned , their potencies are thought to be almost identical
The speaker will introduce basic treatment methods focusing on the forehead, glabellar, and eye area using products used in Korea, and will share the experience so far from a personal perspective, focusing on facial wrinkles using fillers and areas frequently treated in Koreans. Based on over 20 years of experience, I would like to introduce a safe and effective treatment method.


[Lifting and Wrinkles Treatment Using Threads]

Aging signs appear as wrinkles, volume loss, and drooping, and surgical methods, HIFU, RF lifting, thread lifting, and Botox & filler injection are commonly used as treatments.
We want to improve wrinkles and talk about lifting with a focus on thread.
When discussing lifting with thread, two things must be remembered: tighting mainly uses monifilament, and lifting uses thread with a cog. It is injected into the lower dermis with free-floating threads, and uses threads ranging from simple monofilanet threads to twin, screw, and tornado types, without anchoring at any point.
In the actual procedure, the injection is actually in the lower dermis, not the SMAS layer. In other words, the outline is corrected by touching the fibrous septae, and secondarily, type 1 collagen proliferation is induced.
Step by step, all threads are injected in each area at once, and when thread insertion is completed, the syringe is withdrawn and removed, leaving the PDO thread under the skin. This method induces collagen and ellastin proliferation in the lower dermis, resulting in improved skin elasticity and texture.
Next, I would like to change the topic and talk about actual thread lifting by correcting fat loss and repositioning in actual aging.
As a phenomenon of aging, the malar fat pad is shown to fall off, and at the same time, the ligaments are also loosened, and the shallow and deep fat layers are reduced and drooping.
I would like to say that the key to the results of the procedure I am introducing is how to effectively raise the malar fat pad. Here's something to think about. Although lifting using threads is the most effective, you may not prefer thread lifting procedures due to increased down time, swelling, and pain. At this time, a lifting effect can be achieved at the same time by filling the upper part of the malar bone with fat volume or by applying PLLA and hyaluronic acid filler to expand the volume. We need to think about ways to correct sagging muscles and fat volume just by lifting, and ways to provide a lifting effect by filling with filler.
Subperiosteal midface dissection is a concept that repositions the entire muscle and soft tissue tissue. Personally, my goal is to run the thread under the orbicularis oculi muscle to redrap the orbital-malar ligament and malar fat. Subperiosteal midface dissection is a traditional surgical treatment, but mid-face lifting using threads is a concept that repositions the entire muscle and soft tissue tissue. orbicualris muscel and zygomaticus major. You can inject a thread into the space between minor muscles. The purpose is to lift and redrap the orbicularis oculi. Once the procedure is completed, passive septal tightening is possible.
The procedure is to puncture the temporalis muscle with local anesthesia, insert a thread using an 18-gauge needle, then pierce the malar fat tissue with a long introducer, remove the thread, and then cut it.
Using the malar fat pad as a vehicle for lifting, the midface correction with purse string sutures appears to be effective, so this technique can be considered as a valuable alternative to other mid-face rejuvenation techniques
Although some younger patients with good skin quality may benefit from threaded subcutaneous injections, most patients benefit from barbed sutures that support the mid-face soft tissues.
When performing the procedure, a suture is tied to a long straight needle exiting laterally from the temporal lobe to the nasolabial fold and placement is performed.
Today's speaker must remember two things when discussing lifting with thread. Tightening mainly uses monifilament, and lifting uses thread with a cog. At this time, this allows the "shish kebob" effect to be created by incorporating the barb suture as it passes through the periosteum, SMAS, sub-orbicularis oculi fat (SOOF), malar fat pad, and skin. This suspension suture results in strong correction of the nasolabial folds, strengthening of the malar region, lifting of the midface, and consequently shortening of the vertical height of the lower eyelid.


[Procedures For Forehead and Temple Augmentation Using PLLA with HA]

Purpose: Recently, a procedure to create a three-dimensional effect by injecting volume into the forehead has become popular among Korean women. And as we age, the temple area shrinks and soft tissue decreases, which is also a major aspect of mid-facial aging. Therefore, cosmetic interest in wanting volume in this area is increasing. It is best to make the forehead convexity thick without any dents overall. If you add volume to the temple area, you will look younger and your facial lines will look softer. In fact, a lot of hyaluronic acid filler has been injected recently to expand the volume of the forehead and temples. Although the injection method is simple and easy, over time, the defect of the surface being uneven appears, so re-injection is often required or it is unsatisfactory. Therefore, we would like to introduce a dual filler injection method that is relatively easy to inject, has good spreadability, and can increase the amount of collagen while maintaining good volume.
Method: For forehead depression, use a filler with high viscosity that can have a volumizing effect on the periosteum. Fillers with high viscosity provide good volume, but are technically difficult to inject evenly throughout the forehead. Therefore, most people use monophasic fillers, which have good spreadability. Although they are easier to shape, they have the disadvantage of having an uneven surface over time, so they often have to be re-injected or are unsatisfactory. There are several ways to inject the temple, but the author prefers the method of injecting into loose areolar tissue.
Result: Using two types of filler, we tried to provide a contour improvement effect by injecting filler into the space to be filled in the forehead and temple areas. I want to show you a simple method. By filling this space with filler, natural forehead volume is formed, forehead sagging is improved, and bumpy side effects are reduced. Also, with the use of dual filler, the phenomenon of aging, such as sagging of the temples, was greatly improved by using a collagen production stimulator and hyaluronic acid filler at the same time.

- Director, SeoulLeaguer Dermatology
- Director of Stem Cell Therapy Association of Korea
- Chief of the Facial Wrinkle Contour Laboratory
- Doctor of Ruiri Cosmetic Surgery Clinic in Shanghai
- Director of the Facial Contour Laboratory
Chairman MD of the Mirror Cosmetic Clinic

• Title : [Lasers & EBD] Clinico-Pathol-Radiological Correlation of Common Vascular Lesions for Implications on therapeutic approach
• Date : 11/30(Sat), at 15:40
• Room : EXCO Room 322

[Clinico-Pathol-Radiological” Correlation of Vascular Lesions for Implication on Therapeutic Approach]

The accurate diagnosis of congenital and acquired vascular lesions is very difficult infrequently, but is mandatory because it’s correct diagnosis is essential prerequisites for appropriate management. In addition to classification based on clinical and pathological viewpoints, radiological information is also important sometimes to make their correct diagnosis. Considering dermatologist who is familiar to clinical and/or pathologic facet but not radiological facet of vascular lesion including tumors and malformations, the mis-diagnosis and consequently mis-management may be unavoidable partly while dealing them.
Herein, I will try to show several cases by showing their holistic information based on ISSVA (International Society for the Study of Vascular Anomalies, http://www.issva.org) scheme and will show some situations as follows;.
1) Infantile hemangioma and its simulants; IH, TA, CH,
2) Angiokeratoma and its deeper counterpart, verrucous hemangioma
3) Portwine stain (nevus flammeus) and its simulants, including especially arteriovenous malformation of stage 1~2

- Clinical fellow, National Skin Centre(Singapore), 1995
- Clinical Fellow(Phlebology), Free University of Berlin, Berlin, Germany, 2000
- Won Poster Award, 63th Korean Dermatological Association, 2011
- Won Poster Award, 22nd World Congress of Dermatology, 2011
- Former President, Korean Society of Aesthetic and Dermatologic Surgery
(KSDS)
- Former President, Korean Society of Dermatopathology (KSDP)
- President, Korean Society of Skin Cancer (KSSC)

• Title : [Injectables] Facial Volumizing Technique using Collagen Synthesis Accelerator (PLLA)
• Date : 11/30(Sat), at 11:10
• Room : EXCO Room 322

• Title : [Live Surgery] Collagen Stimulator Filler
• Date : 12/01(Sun), at 09:00
• Room : Room 322 (JCI allforskin Dermatologic Hospital)

[Facial volumizing technique using collagen synthesis accelerator (PLLA)]

PLLA (Poly L lactic acid) has become one of the most promising biomaterials because of its advantages, such as biocompatibility, biodegradability, and minimal inflammatory inductive property. PLLA is superior to conventional classic fillers in terms of stability and effect persistence; thus, it is thought that not only the face but also any part of the body will be used more as a supplement to fill tissue defects. The histological findings of the sites where the PLLA was administered, a weak inflammatory reaction, infiltration of foreign body giant cells, and elongated fibroblasts were observed, so the paracrine effects of foreign body giant cells are presumed to be the central mechanistic features resulting in increases in the production of new collagen over the months. But, it was expected that there would be other mechanisms as the volume filling effect tended to appear too quickly to be viewed only as a paracrine effect. So we studied to see if the PLLA directly increases collagen synthesis in cultured dermal fibroblasts. Human dermal fibroblast cell line (HS68) and preadipocyte cell line( 3T3 L1) were treated with PLLA, and type I , IVcollagen gene expressions were evaluated using RT-PCR, ELISA and Western-blot analyses. The results showed that PLLA directly stimulating on dermal fibroblasts leading to a significant increase in type I collagen gene expression and protein synthesis and also PLLA increases the stability of fat by directly affecting fat cells. Hence, various signaling pathways are involved in fibroblast migration and promotes collagen synthesis, resulting in volumne replacement and cutaneous wound healing, so further research about the effects of PLLA on other extracellular matrix components is very hopeful in the future. We think that PLLA could be effective if it is applied to the treatment of localized lipoatrophy and secondary atrophic change such as scleroderma or lupus, trauma, etc. However, since we do not know the precise mechanism, we can’t exclude the possibility of causing progressive fibrotic changes such as keloid or hypertrophic scar when used excessively, so, we should always pay attention when using PLLA.

- Professor, Department of dermatology, Keimyung University Dongsan hospital
- Former Director, Joseph Dermatologoc Clinic Daegu, Korea
- Executive director of ethics and laws of the Korean Dermatological Association
- Audit committee member of the Korean society of the photomedicine

• Title : Japanese “Omakase” culture in aesthetic medicine:Personalized combination treatments.
• Date : 11/30(Sat), at 14:00
• Room : EXCO Room 322

• Title : Off-label Dermatologic Use of Botulinum Toxin
• Date : 11/30(Sat), at 11:30
• Room : EXCO Room 322

[Off-label dermatologic use of botolinum toxin]

In this lecture, we aim to provide an introduction to the various uses of Botulinum toxin, supported by a review of the literature. We will begin with a brief overview of Botulinum toxin and its mechanism of action. While Botulinum toxin has traditionally been utilized for the purpose of improving wrinkles, its applications extend far beyond that. This lecture will explore several diverse application areas, including:

1. Wound Healing and Scar Prevention: Introduction about how Botulinum toxin has been employed in wound healing and scar prevention, highlighting its potential benefits in these areas.

2. Treatment of Oily Skin and Wide Pores: Botulinum toxin's role in addressing oily skin and minimizing wide pores will be discussed, shedding light on its effectiveness in managing these dermatological concerns.

3. Management of Facial Flushing, Particularly in Rosacea: Introduction about the use of Botulinum toxin in managing facial flushing, with a specific focus on its application in patients with Rosacea.

4. Botulinum Toxin in Androgenic Alopecia: Lastly, we will review the use of Botulinum toxin in the context of Androgenic alopecia, showcasing its potential utility in this condition.

Through this comprehensive explanation, this lecture aim to provide insights into the versatile applications of Botulinum toxin in various medical and cosmetic domains.

- Kyungpook National University Assistant professor 2021-Present
- Department of dermatology, Kyungpook National University School of
Medicine 2021-Present
- NAMSONG Academic Award (Korean Dermatological Association), 2023

• Title : TBD- Multi-effector of lifting: “Meshfill“
• Date : 11/30(Sat), at 16:20
• Room : EXCO Room 322

• Title : TBD - Principles and Methods of HIFU and Monopolar Radiofrequency Treatment
• Date : 12/01(Sun), at 11:00
• Room : Room 322 (JCI allforskin Dermatologic Hospital)

[Threads] Multi-effector of lifting: “Meshfill“

As aging progresses, many and diverse changes of face occur across multiple
layers, including not only the skin but also the fat layer, muscles, and facial
skeleton.

In order to treat this aging process, the treatment methods is needed that not
only improves the skin's intrinsic elasticity, but also restores volume loss due to
loss of fat layer, sagging of the supporting ligaments of connective tissue, and
volume loss in muscles and skeleton.

I would like to introduce the world's first thread with a unique multi-mesh
structure that goes beyond the skin pulling effect and skin regeneration effect
that relies on the tensile force of general thread lifting. It can effectively and
easily treat not only the skin pulling effect and skin regeneration effect of the
thread itself, but also volume loss of the fat layer and sagging of the supporting ligaments of connective tissue.

I would also introduce more effective and longer-lasting treatment methods by
treating it in parallel with other lifting and regenerative treatment methods, such as ultrasonic high-frequency equipment targeting the skin, filler targeting fat layer volume reduction, and toxin targeting muscle and contour.

- Director, Oh Kim's Dermatology Seoul
- Ph.D Korea University
- Nevada State of University, Visiting Scholarship

• Title : Wise treatment of various scars using laser
• Date : 11/30(Sat), at 09:40
• Room : EXCO Room 322

[Wise treatment of various scars using laser]

Scar formation after wound healing is a consequence of a repair mechanism that replaces the missing normal tissue with extracellular matrix. But, skin wounds on early mammalian embryos heal perfectly without scars. Early mammalian embryos have less of an inflammatory response than that of adults because embryonic wounds consist of less differentiated inflammatory cells. Thus, reducing inflammation during early wound healing is a key for preventing scar formation.
Based on these points, analyzing the healing stages of scars in pathological lesions and establishing appropriate treatment methods requires a considerable amount of experience. Especially for scars or wounded areas that have recently undergone surgery, it is necessary to carefully analyze the anatomical location, the extent of inflammation and erythema, and choose the appropriate type of laser. During the treatment, unexpected occurrences such as the development of erythema, discomfort, or hypertrophic changes in the scar area may arise. In such cases, it is crucial to temporarily suspend the treatment and wait for further assessment.
I want to present on the application of various lasers and skin boosters used in scar treatment and discuss at which stage each should be applied.

- Director, Gounmi Dermatologic Clinic
- Former Chairman of department of dermatology, Keimyung Univ. School of
medicine
- Visiting Research track, Osaka University, Division of Gene Therapy Science;
Bone marrow Stem cell application to Skin
- Visiting Scholar, Tokyo University; Adipose tissue derived stem cell
application to skin
- Members of Korean Dermatological assiociation
- Members of Korean Society of Psoriasis

• Title : Cadaver Workshop
• Date : 11/30(Sat), at 08:00
• Room : Keimyung University Dongsan Hospital

• Title : Treatment of various forms of cysts in dermatology
• Date : 11/30(Sat), at 13:00
• Room : EXCO Room 322

• Title : Recent Advances in the Systemic Treatment of Atopic Dermatitis and Alopecia Areata
• Date : 11/30(Sat), at 13:20
• Room : EXCO Room 322

• Title : Dermatolocial Application with Botulinum Toxin
• Date : 11/30(Sat), at 14:40
• Room : EXCO Room 322

• Title : Treatment of keloid
• Date : 11/30(Sat), at 16:40
• Room : EXCO Room 322

• Title : [Live Surgery] Principles and Methods of HIFU and Monopolar Radio frequency Treatment
• Date : 12/1(Sun) at 13:00
• Room : Room 322 (JCI allforskin Dermatologic Hospital)

• Title : [Live Surgery] Treatment of Various Pigmentary Disorders using Laser Devices
• Date : 12/01(Sun), at 14:00
• Room : Room 322 (JCI allforskin Dermatologic Hospital)

[Treatment of various pigmentary disorders using laser devices]

Treatment of pigmentary disorder using 1064nm picosecond Nd:YAG laser (Discovery Pico, Quanta.), 694nm Ruby laser(Q Plus-C ruby, Quanta.) and CO2 laser

- Kyungpook National University Hospital, Dermatology 2014.5 – 2015.2
- JCI Allforskin Dermatology Hospital 2015.3 - present